What are the side effects of nicosamide?
Nikethamide is a central nervous system stimulant that has been used to treat respiratory depression and central respiratory failure. With the development of medicine, its clinical application has gradually decreased, but understanding its side effects still has important reference value. The following is a detailed analysis of the side effects of nicosamide.
1. Introduction to Nikoshami

Nicotsamide increases the frequency and depth of breathing by stimulating the medulla oblongata respiratory center. However, due to its obvious side effects, it is now mostly replaced by safer drugs. The following are its main pharmacological effects:
| Mechanism of action | Indications | Usage restrictions |
|---|---|---|
| excited respiratory center | central respiratory depression | has been gradually eliminated |
2. Common side effects
Nicotsamide may cause the following adverse reactions:
| Side effect type | Specific performance | probability of occurrence |
|---|---|---|
| nervous system | Restlessness, tremors, twitching | Middle to high |
| cardiovascular system | Heart palpitations, elevated blood pressure | in |
| digestive system | Nausea, vomiting | low |
3. Serious side effects and contraindications
Overuse or special populations may present the following risks:
| risk level | Symptoms | Countermeasures |
|---|---|---|
| high risk | Convulsions, arrhythmia | Stop medication immediately and seek medical advice |
| Taboo groups | Epilepsy patients, pregnant women | Prohibited use |
4. Drug interactions
Taking nicosamide with other medicines may increase the side effects:
| Combination drugs | Interaction results |
|---|---|
| Other central stimulants | Poison stacking |
| antihypertensive drugs | Reduced efficacy |
5. Clinical Use Suggestions
1. Strictly follow the doctor’s instructions to control the dosage and avoid long-term use.
2. Monitor heart rate, blood pressure and neurological symptoms during medication.
3. If serious adverse reactions occur, you must stop taking the drug immediately and seek medical help.
6. Summary
The use of nicosamide in modern medicine has been greatly reduced due to the significant risk of side effects. Patients should fully understand the potential hazards when using it and give priority to safer alternative drugs.
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